Testosterone Replacement Therapy

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A recent New England Journal of Medicine article focuses on a case vignette about a 61 year old gentleman (Martin) who complains of low energy, low libido and a decreased ability to play sports.  Martin´s physical is unremarkable with the only noteworthy fact is that he is obese.  His blood results shows normal hematocrit, normal fasting glucose and normal thyroid function.  His prostate specific antigen (PSA) is 3.5 which is stable comparing it to a level taken a year ago.  What is noteworthy, is a testosterone level of 275 ng/deciliter (normal range is 300-1200 ng/deciliter).

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Progesterone and anti-aging and wellness therapy

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Synthetic progesterone or natural progesteroneProgesterone is one of the sex hormones and is made in the ovaries before menopause.  After menopause, some progesterone is made in the adrenal glands.  In a woman, there are many reasons why she can be deficient in progesterone.  In fact, symptoms of progesterone loss is what frequently brings women to visit their doctor. Progesterone loss symptoms include: anxiety, depression, irritability, mood swings, insomnia, pain, osteoporosis, decreased HDL cholesterol and excessive menstruation.  Causes of progesterone loss include stress, antidepressants, hypothyroidism, diets high in sugar and saturated fat and vitamin deficiencies including vitamin A, B6, Vitamin C and zinc. 

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